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Rekombinanter CD27 Antikörper

CD27 Reaktivität: Human FACS, IHC (f) Wirt: Maus Monoclonal rLPFS2-1611 unconjugated Recombinant Antibody
Produktnummer ABIN6936649
  • Target Alle CD27 Antikörper anzeigen
    CD27 (CD27 Molecule (CD27))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 194
    • 75
    • 54
    • 9
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 111
    • 90
    • 22
    • 11
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 145
    • 92
    • 2
    Monoklonal
    Konjugat
    • 82
    • 24
    • 24
    • 15
    • 13
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD27 Antikörper ist unkonjugiert
    Applikation
    • 154
    • 80
    • 50
    • 39
    • 34
    • 22
    • 19
    • 14
    • 13
    • 13
    • 10
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant human CD22 protein (exact sequence is proprietary)
    Klon
    RLPFS2-1611
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD27 Primärantikörper
  • Applikationshinweise

    Known_Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Ramos cells. Human peripheral blood lymphocytes. Human tonsil and lymph node.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    CD27 (CD27 Molecule (CD27))
    Andere Bezeichnung
    CD27 (CD27 Produkte)
    Hintergrund
    LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7,CD27 (Tumor Necrosis Factor Receptor Superfamily 7)
    Cellular localisation: Cell Surface
    Molekulargewicht
    120kDa
    Gen-ID
    939, 355307
    UniProt
    P26842
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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