CD2 Antikörper
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- Target Alle CD2 Antikörper anzeigen
- CD2
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD2 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Spezifität
- CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
- Kreuzreaktivität (Details)
- Human. Chimpanzee. Baboon. Monkey. Pig.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human CD2 protein
- Klon
- RPA-2-10
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD2 Primärantikörper
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- Applikationshinweise
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Known_Application: Functional Studies (Order Ab without Azide), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: 293T or Jurkat cells. Lymph node and tonsil.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- CD2
- Andere Bezeichnung
- CD2 (CD2 Produkte)
- Synonyme
- CD2 antikoerper, LFA-2 antikoerper, Ly-37 antikoerper, Ly37 antikoerper, SRBC antikoerper, T11 antikoerper, CD2R antikoerper, LFA2 antikoerper, OX-34 antikoerper, OX34 antikoerper, CD2 molecule antikoerper, CD2 antigen antikoerper, Cd2 molecule antikoerper, CD2 antikoerper, Cd2 antikoerper
- Hintergrund
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Erythrocyte receptor, LFA-2, LFA-3 receptor, Ly-37, Lymphocyte function antigen 2, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11,CD2 / Lymphocyte Function Antigen 2 (LFA-2)
Cellular localisation: Cell surface - Molekulargewicht
- 50kDa
- Gen-ID
- 914, 523500
- UniProt
- P06729
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