BTLA Antikörper
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- Target Alle BTLA Antikörper anzeigen
- BTLA (B and T Lymphocyte Associated (BTLA))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser BTLA Antikörper ist unkonjugiert
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Applikation
- ELISA, Coating (Coat)
- Spezifität
- B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human BTLA protein
- Klon
- BTLA-1528
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product BTLA Primärantikörper
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anti-B and T Lymphocyte Associated (BTLA) antibody
BTLA Reaktivität: Human WB, FACS Wirt: Maus Monoclonal 2E4 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 31-157) antibodyBTLA Reaktivität: Human WB, FACS, ELISA, IHC, ICC, Neut Wirt: Maus Monoclonal 5G1G10 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 179-289) antibodyBTLA Reaktivität: Human WB, FACS, ELISA, IHC, ICC, Neut Wirt: Maus Monoclonal 7H3E3 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 221-289) antibodyBTLA Reaktivität: Human, Maus WB, FACS, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA Reaktivität: Human WB, FACS, IF Wirt: Maus Monoclonal 2G2 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 101-150) antibodyBTLA Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal MIH26 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibody (PE)BTLA Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal MIH26 PE
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- Applikationshinweise
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Known_Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Human lymph node or MDAMB468 xenograft.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- BTLA (B and T Lymphocyte Associated (BTLA))
- Andere Bezeichnung
- BTLA (BTLA Produkte)
- Synonyme
- BTLA antikoerper, BTLA1 antikoerper, CD272 antikoerper, A630002H24 antikoerper, B and T lymphocyte associated antikoerper, BTLA antikoerper, Btla antikoerper
- Hintergrund
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B and T lymphocyte associated protein, B and T lymphocyte attenuator, B and T lymphocyte associated, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, BTLA, BTLA_HUMAN, BTLA1, CD272, CD272 antigen, FLJ16065, MGC129743,BTLA
Cellular localisation: Membrane - Molekulargewicht
- 33kDa
- Gen-ID
- 151888, 445162
- Pathways
- Cancer Immune Checkpoints
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