Iba1 Antikörper (AA 1-146)
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- Target Alle Iba1 (IBA1) Antikörper anzeigen
- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
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Bindungsspezifität
- AA 1-146
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Iba1 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Purified fragment of human recombinant AIF1 protein (around aa 1-146) (exact sequence is proprietary)
- Klon
- AIF1-1909
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product IBA1 Primärantikörper
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- Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Lymph Node, Tonsil or Kidney.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
- Andere Bezeichnung
- AIF1 (IBA1 Produkte)
- Synonyme
- AIF-1 antikoerper, IBA1 antikoerper, IRT-1 antikoerper, IRT1 antikoerper, AI607846 antikoerper, D17H6S50E antikoerper, G1 antikoerper, Iba1 antikoerper, Bart1 antikoerper, iba1 antikoerper, mrf-1 antikoerper, fa04b11 antikoerper, wu:fa04b11 antikoerper, AIF antikoerper, AIF1 antikoerper, aif1 antikoerper, allograft inflammatory factor 1 antikoerper, AIF1 antikoerper, Aif1 antikoerper, aif1 antikoerper
- Hintergrund
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Allograft inflammatory factor 1 (AIF1), balloon angioplasty responsive transcription (BART1), IBA1, Interferon responsive transcript 1, Ionized calcium-binding adapter molecule 1, IRT1, Microglia response factor (MRF1),AIF1 / Iba1 (Microglia Marker)
Cellular localisation: Cytoplasmic and Cell Surface - Molekulargewicht
- 17kDa
- Gen-ID
- 199, 76364
- UniProt
- P55008
- Pathways
- Smooth Muscle Cell Migration
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