Transferrin Receptor Antikörper (CF®488A)

Produktnummer ABIN6935764

Produktdetails anti-Transferrin Receptor Antikörper (CF®488A)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist konjugiert mit CF®488A

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Spezifität: It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Aufreinigung: Purified by Protein A/G

Immunogen: Human thymocytes (T-cells)

Klon: 66IG10

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: TFRC (TFRC Produkte)

Synonyme: Trfr antikoerper, LOC100219280 antikoerper, tfr antikoerper, cd71 antikoerper, tfr1 antikoerper, trfr antikoerper, CD71 antikoerper, T9 antikoerper, TFR antikoerper, TFR1 antikoerper, TR antikoerper, TRFR antikoerper, p90 antikoerper, 2610028K12Rik antikoerper, AI195355 antikoerper, AI426448 antikoerper, AU015758 antikoerper, E430033M20Rik antikoerper, Mtvr-1 antikoerper, Mtvr1 antikoerper, transferrin receptor antikoerper, TFRC antikoerper, Tfrc antikoerper, tfrc antikoerper

Molekulargewicht: 85-95kDa (monomer), 190kDa (dimer)

Gen-ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis