CD31 Antikörper (CF®488A)

Produktnummer ABIN6934733

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD31 in FACS, IF und T. Er zeigt eine Reaktivität gegenüber Human, Kaninchen und Affe.

Kurzübersicht für CD31 Antikörper (CF®488A) (ABIN6934733)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reaktivität: Human, Kaninchen, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD31 Antikörper ist konjugiert mit CF®488A

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Klon: C31-7

Produktdetails anti-CD31 Antikörper (CF®488A)

Spezifität: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human CD31 protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Jurkat, CCRF-CEM or K-562 cells. Tonsil, Angiosarcoma.

Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Andere Bezeichnung: PECAM1

Molekulargewicht: ~100kDa (endothelium) and ~130kDa (platelets)'

Gen-ID: 5175

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization