Vimentin Antikörper (CF®488A)
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- Target Alle Vimentin (VIM) Antikörper anzeigen
- Vimentin (VIM)
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Reaktivität
- Human, Schwein, Rind (Kuh), Huhn, Hund, Cat, Ziege
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Vimentin Antikörper ist konjugiert mit CF®488A
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Test (T)
- Spezifität
- This MAb reacts with a 58 kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP's) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a diagnostic tool, however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.
- Keine Kreuzreaktivität
- Maus, Ratte (Rattus)
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant human vimentin protein
- Klon
- VM452
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product VIM Primärantikörper
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- Applikationshinweise
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Positive Control: Jurkat cells, Sarcomas, Melanomas.
Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 100 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- Vimentin (VIM)
- Andere Bezeichnung
- VIM (VIM Produkte)
- Synonyme
- CTRCT30 antikoerper, cb28 antikoerper, vime antikoerper, vim antikoerper, vim1 antikoerper, vim2 antikoerper, VIM antikoerper, Vimentin antikoerper, vim4 antikoerper, vimentin antikoerper, vimentin L homeolog antikoerper, vimentin S homeolog antikoerper, VIM antikoerper, Vim antikoerper, vim antikoerper, vim.L antikoerper, vim.S antikoerper
- Molekulargewicht
- 57-60kDa
- Gen-ID
- 7431
- UniProt
- P08670
- Pathways
- Caspase Kaskade in der Apoptose
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