IGKC Antikörper (CF®488A)

Produktnummer ABIN6934406

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IGKC in IHC, StM und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IGKC Antikörper (CF®488A) (ABIN6934406)

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGKC Antikörper ist konjugiert mit CF®488A

Applikation: Immunohistochemistry (IHC), Staining Methods (StM), Flow Cytometry (FACS)

Klon: KLC709

Produktdetails anti-IGKC Antikörper (CF®488A)

Spezifität: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human IGKC protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu IGKC

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Andere Bezeichnung: IGKC

Molekulargewicht: ~22.5kDa

Gen-ID: 3514

UniProt: P01601, P01834