tau Antikörper (pSer202, pThr205) (APC)

Produktnummer ABIN6932894

Produktdetails anti-tau Antikörper (APC)

Target: tau (tau Protein)

Bindungsspezifität: pSer202, pThr205

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser tau Antikörper ist konjugiert mit APC

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)

Spezifität: Expressed in neurons.,Detects ~79 kDa.

Kreuzreaktivität: Human, Maus

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide of Human Phospho Tau (Ser202/Thr205)

Klon: AH36

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• WB (1:500)
• ICC/IF (1:500)
• IHC (1:500)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:500 dilution of ABIN6932894 was sufficient for detection of Tau in 10 μg Baculovirus by dot blot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu tau

Target: tau (tau Protein)

Andere Bezeichnung: Tau (tau Produkte)

Hintergrund: Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3).

Gen-ID: 4137

UniProt: P10636