tau Antikörper (pSer202, pThr205) (Atto 390)

Produktnummer ABIN6932885

Dieser Anti-tau Antikörper ist ein Kaninchen Monoklonal Antikörper zur Detektion von tau in WB, ELISA, IHC, IF, ICC und DB. Geeignet für Human.

Kurzübersicht für tau Antikörper (pSer202, pThr205) (Atto 390) (ABIN6932885)

Target: tau (tau Protein)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser tau Antikörper ist konjugiert mit Atto 390

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)

Klon: AH36

Produktdetails anti-tau Antikörper (Atto 390)

Bindungsspezifität: pSer202, pThr205

Spezifität: Expressed in neurons.,Detects ~79 kDa.

Kreuzreaktivität: Human, Maus

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide of Human Phospho Tau (Ser202/Thr205)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• WB (1:500)
• ICC/IF (1:500)
• IHC (1:500)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:500 dilution of ABIN6932885 was sufficient for detection of Tau in 10 μg Baculovirus by dot blot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu tau

Target: tau (tau Protein)

Andere Bezeichnung: Tau

Hintergrund: Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3).

Gen-ID: 4137

UniProt: P10636