Cathepsin L Antikörper (AA 71-170) (FITC)
Kurzübersicht für Cathepsin L Antikörper (AA 71-170) (FITC) (ABIN687539)
Target
Alle Cathepsin L (CTSL1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 71-170
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Kreuzreaktivität
- Human, Schwein, Ratte
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Homologie
- Mouse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from mouse capsin L1 proprotein
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
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Andere Bezeichnung
- Cathepsin L
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Hintergrund
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Synonyms: fs, MEP, nkt, Ctsl1, 1190035F06Rik, Cathepsin L1, Cathepsin L, Major excreted protein, p39 cysteine proteinase, Ctsl
Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.
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Gen-ID
- 13039
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UniProt
- P06797
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Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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