TRAP1 Antikörper (AA 501-650) (FITC)
Kurzübersicht für TRAP1 Antikörper (AA 501-650) (FITC) (ABIN686654)
Target
Alle TRAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 501-650
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Kreuzreaktivität
- Ratte
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Homologie
- Human,Mouse,Horse,Chicken,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human HSP75
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1792-1803, (2016) (PubMed).
: "
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TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1792-1803, (2016) (PubMed).
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- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
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Andere Bezeichnung
- Hsp75/Trap1
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Hintergrund
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Synonyms: HSP75, HSP 75, HSP90L, TRAP-1, Heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP1
Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
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Gen-ID
- 10131
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UniProt
- Q12931
Target
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