GCN2 Antikörper (pThr899)
Kurzübersicht für GCN2 Antikörper (pThr899) (ABIN684943)
Target
Alle GCN2 (EIF2AK4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pThr899
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Spezifität
- This phosphorylation site is homologous to Thr898 in Mouse and Thr899 in Rat.
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Kreuzreaktivität
- Human
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Homologie
- Mouse,Rat,Dog,Cow,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human GCN2 around the phosphorylation site of Thr899
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcoma." in: Scientific reports, Vol. 5, pp. 11781, (2015) (PubMed).
: "
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Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcoma." in: Scientific reports, Vol. 5, pp. 11781, (2015) (PubMed).
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- GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))
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Andere Bezeichnung
- GCN2
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Hintergrund
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Synonyms: GCN2, PVOD2, Eukaryotic translation initiation factor 2-alpha kinase 4, GCN2-like protein, EIF2AK4, KIAA1338
Background: GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses.
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Gen-ID
- 440275
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UniProt
- Q9P2K8
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Pathways
- ER-Nucleus Signaling, Hepatitis C
Target
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