DOK2 Antikörper (pTyr351) (Biotin)
Quick Overview for DOK2 Antikörper (pTyr351) (Biotin) (ABIN684150)
Target
Alle DOK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr351
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Spezifität
- This phosphorylation site is found at Tyr345 in Human. Due to the highly conserved nature of this sequence with DOK1, this antibody may react with DOK1 when it is phosphorylated at Tyr362 in Human and Tyr361 in Mouse and Rat.
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Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from mouse p56Dok2 around the phosphorylation site of (Tyr351)
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Isotyp
- IgG
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Applikationshinweise
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WB 1:100-1000
IHC-P 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- DOK2
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Andere Bezeichnung
- Dok2
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Hintergrund
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Synonyms: DokR, Frip, Docking protein 2, Dok-related protein, Dok-R, Downstream of tyrosine kinase 2, IL-four receptor-interacting protein, p56(dok-2), Dok2
Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.
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Gen-ID
- 13449
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UniProt
- O70469
Target
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