DOK2 Antikörper (pTyr351) (Biotin)

Produktnummer ABIN684150

Dieses Anti-DOK2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DOK2 in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Human und Maus.

Kurzübersicht für DOK2 Antikörper (pTyr351) (Biotin) (ABIN684150)

Target: DOK2

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOK2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DOK2 Antikörper (Biotin)

Bindungsspezifität: pTyr351

Spezifität: This phosphorylation site is found at Tyr345 in Human. Due to the highly conserved nature of this sequence with DOK1, this antibody may react with DOK1 when it is phosphorylated at Tyr362 in Human and Tyr361 in Mouse and Rat.

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse p56Dok2 around the phosphorylation site of (Tyr351)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DOK2

Target: DOK2

Andere Bezeichnung: Dok2

Hintergrund:

Synonyms: DokR, Frip, Docking protein 2, Dok-related protein, Dok-R, Downstream of tyrosine kinase 2, IL-four receptor-interacting protein, p56(dok-2), Dok2

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.

Gen-ID: 13449

UniProt: O70469