LAMP2 Antikörper

Produktnummer ABIN6796359

Der Maus Monoklonal Anti-LAMP2-Antikörper wurde für WB, FACS, IP und IF validiert. Er ist geeignet, LAMP2 in Proben von Human, Hund und Nerz zu detektieren.

Kurzübersicht für LAMP2 Antikörper (ABIN6796359)

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reaktivität: Human, Hund, Nerz

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LAMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: AC17

Produktdetails anti-LAMP2 Antikörper

Spezifität: Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy.

Keine Kreuzreaktivität: Maus, Ratte (Rattus)

Aufreinigung: Protein G purified

Immunogen: MDCK (Madin-Darby Canine Kidney) cells.

Type of Immunogen: Cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo, IF, IP, WB (1:100 - 1:500)

Kommentare:

Target Species of Antibody: Dog

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu LAMP2

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Andere Bezeichnung: LAMP2 / CD107b

Hintergrund: Name/Gene ID: LAMP2
Family: Cancer

Synonyms: LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2

Gen-ID: 3920

Pathways: Autophagie