CD51 Antikörper (AA 51-150)

Produktnummer ABIN678983

Der Kaninchen Polyklonal Anti-CD51-Antikörper wurde für WB, FACS, ELISA, IHC (fro), IF (p), IF (cc) und IHC (p) validiert. Er ist geeignet, CD51 in Proben von Human und Maus zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für CD51 Antikörper (AA 51-150) (ABIN678983)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD51 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CD51 Antikörper

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin alpha V

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CD51 Antikörper (ABIN678983)

Agarwal, Loder, Sorkin, Li, Shrestha, Zhao, Mishina, James, Levi: "Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification." in: Stem cells (Dayton, Ohio), Vol. 34, Issue 6, pp. 1692-701, (2016) (PubMed).

Ulmasov, Neuschwander-Tetri, Lai, Monastyrskiy, Bhat, Yates, Oliva, Prinsen, Ruminski, Griggs: "Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice." in: Cellular and molecular gastroenterology and hepatology, Vol. 2, Issue 4, pp. 499-518, (2016) (PubMed).

Details zu CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Andere Bezeichnung: Integrin alpha V/CD51

Hintergrund:

Synonyms: CD51, MSK8, VNRA, VTNR, Integrin alpha-V, Vitronectin receptor subunit alpha, ITGAV

Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Gen-ID: 3685

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex