Caldesmon Antikörper (pSer789)
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- Target Alle Caldesmon (CALD1) Antikörper anzeigen
- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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Bindungsspezifität
- pSer789
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Reaktivität
- Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caldesmon Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Dog,Cow,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Caldesmon around the phosphorylation site of Ser789
- Isotyp
- IgG
- Top Product
- Discover our top product CALD1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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Neuropathy optic glaucomatosa induced by systemic hypertension through activation endothelin-1 signaling pathway in central retinal artery in rats." in: International journal of ophthalmology, Vol. 9, Issue 11, pp. 1568-1577, (2016) (PubMed).
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Neuropathy optic glaucomatosa induced by systemic hypertension through activation endothelin-1 signaling pathway in central retinal artery in rats." in: International journal of ophthalmology, Vol. 9, Issue 11, pp. 1568-1577, (2016) (PubMed).
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- Target
- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
- Andere Bezeichnung
- Caldesmon (CALD1 Produkte)
- Synonyme
- CDM antikoerper, H-CAD antikoerper, HCAD antikoerper, L-CAD antikoerper, LCAD antikoerper, NAG22 antikoerper, l-Cad antikoerper, 4833423D12Rik antikoerper, AI195384 antikoerper, AV071549 antikoerper, AW536160 antikoerper, C920027I18Rik antikoerper, CALD1 antikoerper, Caldesmon antikoerper, caldesmon 1 antikoerper, CALD1 antikoerper, Cald1 antikoerper
- Hintergrund
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Synonyms: Caldesmon S789, Caldesmon Ser789, p-Caldesmon S789, p-Caldesmon Ser789, p-Caldesmon Ser789, CAD, CALD 1, CALD1, CALD1_HUMAN, Caldesmon 1, Caldesmon 1 Isoform 1, Caldesmon 1 Isoform 2, Caldesmon 1 Isoform 3, Caldesmon 1 Isoform 4, Caldesmon 1 Isoform 5, Caldesmon, Caldesmon1, CDM, H CAD, HCAD, L CAD, LCAD, MGC21352, NAG22.
Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jul 2008].
- Gen-ID
- 800
- Pathways
- Myometrial Relaxation and Contraction
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