CD33 Antikörper (AA 261-364)

Produktnummer ABIN676958

Der Kaninchen Polyklonal Anti-CD33-Antikörper wurde für FACS, WB, ELISA, IHC (fro), IF (p), IF (cc) und IHC (p) validiert. Er ist geeignet, CD33 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für CD33 Antikörper (AA 261-364) (ABIN676958)

Target: CD33

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD33 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CD33 Antikörper

Bindungsspezifität: AA 261-364

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD33

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CD33 Antikörper (ABIN676958)

Shi, Jiang, Li, Shan, Li, An, Yang, Xu: "Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo." in: Journal of hematology & oncology, Vol. 6, Issue 1, pp. 7, (2013) (PubMed).

An, Shi, Wei, Hua, Ci, Jiang, Li, Wu, Hui, Yang, Xu: "The ROS/JNK/ATF2 pathway mediates selenite-induced leukemia NB4 cell cycle arrest and apoptosis in vitro and in vivo." in: Cell death & disease, Vol. 4, pp. e973, (2013) (PubMed).

Details zu CD33

Target: CD33

Andere Bezeichnung: CD33

Hintergrund:

Synonyms: p67, SIGLEC3, SIGLEC-3, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, gp67, CD33

Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Gen-ID: 945

UniProt: P20138