UCP1 Antikörper (AA 101-200)

Produktnummer ABIN675413

Der Kaninchen Polyklonal Anti-UCP1-Antikörper wurde für WB, ELISA, IHC (p), FACS, IF (cc), IF (p) und IHC (fro) validiert. Er ist geeignet, UCP1 in Proben von Human, Maus, Ratte und Ziege zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für UCP1 Antikörper (AA 101-200) (ABIN675413)

Target: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Reaktivität: Human, Maus, Ratte, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UCP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-UCP1 Antikörper

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Ziege, Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UCP-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-UCP1 Antikörper (ABIN675413)

Hou, Shi, Cao, Xu, Hu, Wang: "Pig has no uncoupling protein 1." in: Biochemical and biophysical research communications, Vol. 487, Issue 4, pp. 795-800, (2017) (PubMed).

Sun, Zeng, Cao, Song, Zhang, Liu: "Vibration Training Triggers Brown Adipocyte Relative Protein Expression in Rat White Adipose Tissue." in: BioMed research international, Vol. 2015, pp. 919401, (2015) (PubMed).

Lu, Ji, Zhang, Zhang, Zhang, An, Liu, Zheng: "Resistance to obesity by repression of VEGF gene expression through induction of brown-like adipocyte differentiation." in: Endocrinology, Vol. 153, Issue 7, pp. 3123-32, (2012) (PubMed).

Details zu UCP1

Target: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Andere Bezeichnung: UCP-1

Hintergrund:

Synonyms: Ucp, Slc25a7, AI385626, Mitochondrial brown fat uncoupling protein 1, UCP 1, Solute carrier family 25 member 7, Thermogenin, Ucp1

Background: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.

Gen-ID: 22227

UniProt: P12242

Pathways: Proton Transport, Brown Fat Cell Differentiation