NLRP3 Antikörper (AA 158-207)

Produktnummer ABIN6749780

Der Kaninchen Polyklonal anti-NLRP3 Antikörper (ABIN6749780) detektiert spezifisch NLRP3 in WB, IHC und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Hund und Affe.

Kurzübersicht für NLRP3 Antikörper (AA 158-207) (ABIN6749780)

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Reaktivität: Human, Hund, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NLRP3 Antikörper

Bindungsspezifität: AA 158-207

Spezifität: Human NLRP3. Immunogenic peptide shares 75 % homology with the mouse sequence. The antibody has not been specifically tested with mouse samples at this time. Cross-reactivity or lack thereof therefore cannot be guaranteed.

Homologie: Percent identity by BLAST analysis: Human (100%) Horse, Pig (92%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa158-207 of human NLRP3 (Q96P20, NP_004886). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Galago, Bovine, Rabbit, Horse, Pig (92%), Bat (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 - 10 μg/mL), WB

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Details zu NLRP3

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Andere Bezeichnung: NALP3 / NLRP3

Hintergrund: Name/Gene ID: NLRP3

Synonyms: NLRP3, AGTAVPRL, AII, C1orf7, Caterpiller protein 1.1, Cryopyrin, FCAS, FCU, PYPAF1, NALP3, CIAS1, CLR1.1, MWS

Gen-ID: 114548

NCBI Accession: NP_004886

UniProt: Q96P20

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome