FRZB Antikörper (AA 59-108)

Produktnummer ABIN6746384

Dieser Anti-FRZB Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FRZB in WB. Geeignet für Human, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Fledermaus, Affe, Schwein und Xenopus laevis. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für FRZB Antikörper (AA 59-108) (ABIN6746384)

Target: FRZB (Frizzled-Related Protein (FRZB))

Reaktivität: Human, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Fledermaus, Affe, Schwein, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FRZB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FRZB Antikörper

Bindungsspezifität: AA 59-108

Spezifität: Human FRZB

Homologie: Percent identity by BLAST analysis: Human, Rat, Horse, Pig, Xenopus (100%) Mouse, Zebrafish (92%) Chicken (85%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa59-108 of human FRZB (Q92765, NP_001454). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Rat, Elephant, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Xenopus (100%), Mouse, Zebrafish (92%), Hamster, Zebra finch, Chicken (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Not recommended for: IHC-P

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Referenzen für anti-FRZB Antikörper (ABIN6746384)

Kryl, Yacoubian, Haapasalo, Castren, Lo, Barker: "Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 14, pp. 5823-33, (1999) (PubMed).

Gomeza, Joly, Kuhn, Knöpfel, Bockaert, Pin: "The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins." in: The Journal of biological chemistry, Vol. 271, Issue 4, pp. 2199-205, (1996) (PubMed).

Tanabe, Masu, Ishii, Shigemoto, Nakanishi: "A family of metabotropic glutamate receptors." in: Neuron, Vol. 8, Issue 1, pp. 169-79, (1992) (PubMed).

Masu, Tanabe, Tsuchida, Shigemoto, Nakanishi: "Sequence and expression of a metabotropic glutamate receptor." in: Nature, Vol. 349, Issue 6312, pp. 760-5, (1991) (PubMed).

Details zu FRZB

Target: FRZB (Frizzled-Related Protein (FRZB))

Andere Bezeichnung: SFRP-3 / FRZB

Hintergrund: Name/Gene ID: FRZB
Subfamily: Frizzled

Synonyms: FRZB, FRZB-1, FIZ, FRE, FRITZ, Fritz and frizzled, Frizzled homolog-related, FRP-3, FRZB-PEN, HFIZ, FRP, FZRB, SFRP-3, SRFP3, OS1, Frezzled, Frizzled related protein 3, Frizzled-related protein, Frizzled-related protein 1, FRZB1, SFRP3

Gen-ID: 2487

NCBI Accession: NP_001454

UniProt: Q92765

Pathways: WNT Signalweg, Positive Regulation of fat Cell Differentiation