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Estrogen Receptor alpha Antikörper (C-Term)

ESR1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6746024
  • Target Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Bindungsspezifität
    • 30
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    C-Term
    Reaktivität
    • 464
    • 167
    • 160
    • 17
    • 16
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 374
    • 98
    • 1
    Kaninchen
    Klonalität
    • 356
    • 118
    • 1
    Polyklonal
    Konjugat
    • 213
    • 32
    • 21
    • 19
    • 15
    • 9
    • 9
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    • 4
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    • 4
    • 4
    • 1
    • 1
    Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert
    Applikation
    • 341
    • 158
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    • 94
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    • 54
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    • 15
    • 9
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    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    Human ESR1 / Estrogen receptor
    Homologie
    Percent identity by BLAST analysis: Human (100%).
    Aufreinigung
    Immunoaffinity purified
    Immunogen
    Synthetic peptide from C-Terminus of human ESR1 (P03372, NP_000116). Percent identity by BLAST analysis: Human (100%), Chimpanzee, Gorilla (92%), Baboon, Monkey (85%), Gibbon (84%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product ESR1 Primärantikörper
  • Applikationshinweise
    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Distilled water
    Konzentration
    Lot specific
    Buffer
    Lyophilized from PBS with 2 % sucrose
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • He, Ting: "A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6034-45, (2002) (PubMed).

    Morgan, Thorburn, Pandolfi, Thorburn: "Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms." in: The Journal of cell biology, Vol. 157, Issue 6, pp. 975-84, (2002) (PubMed).

    Yount, Afshar, Ries, Korn, Shalev, Basila, McCormick, Haas-Kogan: "Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells." in: Oncogene, Vol. 20, Issue 22, pp. 2826-35, (2001) (PubMed).

  • Target
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Andere Bezeichnung
    ER Alpha / Estrogen Receptor (ESR1 Produkte)
    Hintergrund
    Name/Gene ID: ESR1
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha
    Gen-ID
    2099
    NCBI Accession
    NP_000116
    UniProt
    P03372
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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