Serotonin Receptor 1A Antikörper (N-Term)

Produktnummer ABIN6736400

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Serotonin Receptor 1A in WB, IHC und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Serotonin Receptor 1A Antikörper (N-Term) (ABIN6736400)

Target: Serotonin Receptor 1A (HTR1A)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Serotonin Receptor 1A Antikörper

Bindungsspezifität: N-Term

Marke: IHC-plus™

Spezifität: Human HTR1A / 5-HT1A

Homologie: Percent identity by BLAST analysis: Human (100%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide from N-Terminus of human HTR1A (P08908, NP_000515). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%), Chimpanzee (92%), Monkey (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (2.5 μg/mL), WB (0.06 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Details zu Serotonin Receptor 1A

Target: Serotonin Receptor 1A (HTR1A)

Andere Bezeichnung: HTR1A / 5-HT1A Receptor

Hintergrund: Name/Gene ID: HTR1A
Subfamily: Serotonin
Family: GPCR

Synonyms: HTR1A, 5-HT-1A, 5HT1a, 5-HT1a receptor, 5HT1ar, 5HT1A receptor, 5-HT1A, ADRBRL1, ADRB2RL1, PFMCD, Serotonin 5-HT-1a receptor, Serotonin type 1a receptor, Serotonergic type 1A receptor, G-21, Serotonin 1a receptor, Serotonin receptor 1A

Gen-ID: 3350

NCBI Accession: NP_000515

UniProt: P08908

Pathways: JAK-STAT Signalweg, Synaptic Membrane, Feeding Behaviour