MCOLN1 Antikörper (AA 101-150)

Produktnummer ABIN214172

Der Kaninchen Polyklonal Anti-MCOLN1-Antikörper wurde für WB, IHC und IHC (p) validiert. Er ist geeignet, MCOLN1 in Proben von Human, Hund, Schwein, Kaninchen, Fledermaus und Affe zu detektieren.

Kurzübersicht für MCOLN1 Antikörper (AA 101-150) (ABIN214172)

Target: MCOLN1 (Mucolipin 1 (MCOLN1))

Reaktivität: Human, Hund, Schwein, Kaninchen, Fledermaus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCOLN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MCOLN1 Antikörper

Bindungsspezifität: AA 101-150

Marke: IHC-plus™

Spezifität: Human MCOLN1 / Mucolipin 1

Homologie: Percent identity by BLAST analysis: Human, Dog, Rabbit, Pig (100%) Rat, Bovine, Horse, Guinea pig (92%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa101-150 of human MCOLN1 (Q9GZU1, NP_065394). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Elephant, Dog, Bat, Rabbit, Pig (100%), Mouse, Rat, Bovine, Horse, Guinea pig (92%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (20 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Details zu MCOLN1

Target: MCOLN1 (Mucolipin 1 (MCOLN1))

Andere Bezeichnung: MCOLN1 / Mucolipin 1

Hintergrund: Name/Gene ID: MCOLN1
Subfamily: Calcium channel - TRP
Family: Ion Channel

Synonyms: MCOLN1, MLIV, ML4, Mucolipidin, Mucolipin 1, MSTP080, Mucolipidosis type IV protein, Mucolipin-1, TRP-ML1, TRPM-L1, MG-2, MST080, TRPML1

Gen-ID: 57192

NCBI Accession: NP_065394

UniProt: Q9GZU1

Pathways: Transition Metal Ion Homeostasis