POMC Antikörper (AA 237-267)

Produktnummer ABIN673209

Dieses Anti-POMC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von POMC in ELISA, FACS, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Maus und Ratte. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für POMC Antikörper (AA 237-267) (ABIN673209)

Target: POMC (Proopiomelanocortin (POMC))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POMC Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-POMC Antikörper

Bindungsspezifität: AA 237-267

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human POMC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-POMC Antikörper (ABIN673209)

Xie, Wang, Li, Chao, Yue: "Early Repeated Administration of CXCR4 Antagonist AMD3100 Dose-Dependently Improves Neuropathic Pain in Rats After L5 Spinal Nerve Ligation." in: Neurochemical research, Vol. 41, Issue 9, pp. 2289-99, (2016) (PubMed).

Nakamoto, Nishinaka, Sato, Mankura, Koyama, Kasuya, Tokuyama: "Hypothalamic GPR40 signaling activated by free long chain fatty acids suppresses CFA-induced inflammatory chronic pain." in: PLoS ONE, Vol. 8, Issue 12, pp. e81563, (2013) (PubMed).

Chao, Lu, Lee, Chen, Wang, Yang, Cheng, Liao, Ro: "Early systemic granulocyte-colony stimulating factor treatment attenuates neuropathic pain after peripheral nerve injury." in: PLoS ONE, Vol. 7, Issue 8, pp. e43680, (2012) (PubMed).

Details zu POMC

Target: POMC (Proopiomelanocortin (POMC))

Andere Bezeichnung: POMC

Hintergrund:

Synonyms: LPH, MSH, NPP, POC, ACTH, CLIP, Pro-opiomelanocortin, POMC, Corticotropin-lipotropin

Background: ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.

Gen-ID: 5443

UniProt: P01189

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour