CTGF Antikörper (AA 221-349)

Produktnummer ABIN672636

Zitiert in 5+ Publikationen. Der Kaninchen Polyklonal anti-CTGF Antikörper (ABIN672636) detektiert spezifisch CTGF in WB, IHC (p), IF (p), IF (cc) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CTGF Antikörper (AA 221-349) (ABIN672636)

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTGF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CTGF Antikörper

Bindungsspezifität: AA 221-349

Verwendungszweck: CTGF Polyclonal Antibody

Kreuzreaktivität: Maus, Ratte

Homologie: Dog,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTGF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CTGF Antikörper (ABIN672636)

Han, Zhang, Zhong, Wang, Zhang, Chen: "MicroRNA-145 Inhibits Cell Migration and Invasion and Regulates Epithelial-Mesenchymal Transition (EMT) by Targeting Connective Tissue Growth Factor (CTGF) in Esophageal Squamous Cell Carcinoma." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 3925-3934, (2017) (PubMed).

Al-Hamilly, Radwan, Abdul-Rahman, Mourad, Grawish: "Biological roles of KGF, CTGF and TGF-β in cyclosporine-A- and phenytoin- induced gingival overgrowth: A comparative experimental animal study." in: Archives of oral biology, Vol. 66, pp. 38-43, (2016) (PubMed).

Ciamporcero, Shen, Ramakrishnan, Yu Ku, Chintala, Shen, Adelaiye, Miles, Ullio, Pizzimenti, Daga, Azabdaftari, Attwood, Johnson, Zhang, Barrera, Pili: "YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage." in: Oncogene, (2015) (PubMed).

Guo, Zhang, Mu, Liu, Yuan, Ren, Wang: "High-salt intake suppressed microRNA-133a expression in Dahl SS rat myocardium." in: International journal of molecular sciences, Vol. 15, Issue 6, pp. 10794-805, (2015) (PubMed).

Tian, Lv, Yang, Zhang, Yu, Zhu, Xiao, Zhu: "Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats." in: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3028-37, (2014) (PubMed).

Details zu CTGF

Target: CTGF (Connective Tissue Growth Factor (CTGF))

Andere Bezeichnung: CTGF

Hintergrund:

Synonyms: CCN2, NOV2, HCS24, IGFBP8, Connective tissue growth factor, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8, CTGF

Background: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

Gen-ID: 1490

UniProt: P29279

Pathways: Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding