CD47 Antikörper (Alexa Fluor 647)
Kurzübersicht für CD47 Antikörper (Alexa Fluor 647) (ABIN6723949)
Target
Alle CD47 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- CD47
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Andere Bezeichnung
- // CD47
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Hintergrund
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Synonyms: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
Background: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
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Gen-ID
- 961, 16423, 29364
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UniProt
- Q08722, Q61735, P97829
Target
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