Angiopoietin 2 Antikörper (AA 401-496)
Kurzübersicht für Angiopoietin 2 Antikörper (AA 401-496) (ABIN671781)
Target
Alle Angiopoietin 2 (ANGPT2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 401-496
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Kreuzreaktivität
- Human
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Homologie
- Mouse,Rat,Dog,Pig,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Angiopoietin 2
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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: "Intranasal administration of human umbilical cord mesenchymal stem cells-conditioned medium enhances vascular remodeling after stroke." in: Brain research, (2015) (PubMed).
: "Is a swine model of arteriovenous malformation suitable for human extracranial arteriovenous malformation? A preliminary study." in: Cardiovascular and interventional radiology, Vol. 36, Issue 5, pp. 1364-70, (2013) (PubMed).
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: "Intranasal administration of human umbilical cord mesenchymal stem cells-conditioned medium enhances vascular remodeling after stroke." in: Brain research, (2015) (PubMed).
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- Angiopoietin 2 (ANGPT2)
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Andere Bezeichnung
- Angiopoietin 2
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Hintergrund
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Synonyms: ANG2, AGPT2, Angiopoietin-2, ANG-2, ANGPT2
Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
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Gen-ID
- 285
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UniProt
- O15123
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Pathways
- RTK Signalweg
Target
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