alpha 1 Adrenergic Receptor Antikörper (AA 201-300)

Produktnummer ABIN670701

Dieses Anti-alpha 1 Adrenergic Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von alpha 1 Adrenergic Receptor in WB, ELISA, FACS, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human, Ratte und Maus. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für alpha 1 Adrenergic Receptor Antikörper (AA 201-300) (ABIN670701)

Target: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha 1 Adrenergic Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-alpha 1 Adrenergic Receptor Antikörper

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Alpha-1A adrenergic receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-alpha 1 Adrenergic Receptor Antikörper (ABIN670701)

Wang, Bai, Cui, Jin, Wang, Jia, Da, Qin: "Effects of estradiol valerate and remifemin on norepinephrine signaling in the brain of ovariectomized rats." in: Neuroendocrinology, Vol. 101, Issue 2, pp. 120-32, (2015) (PubMed).

Chen, Tiong, Tsai, Liao, Yang, Youn, Mai, Chang: "Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency." in: Brain structure & function, (2014) (PubMed).

Sun, Wang, Huang, Cao: "Antihypertensive effect of formononetin through regulating the expressions of eNOS, 5-HT2A/1B receptors and ?1-adrenoceptors in spontaneously rat arteries." in: European journal of pharmacology, Vol. 699, Issue 1-3, pp. 241-9, (2013) (PubMed).

Details zu alpha 1 Adrenergic Receptor

Target: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Andere Bezeichnung: ADRA1A

Hintergrund:

Synonyms: ADRA1C, ADRA1L1, ALPHA1AAR, Alpha-1A adrenergic receptor, Alpha-1A adrenoreceptor, Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c, ADRA1A

Background: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.

Gen-ID: 148

UniProt: P35348

Pathways: AMPK Signaling