DVL1 Antikörper (AA 21-100) (Cy5.5)

Produktnummer ABIN670676

Der Kaninchen Polyklonal Anti-DVL1-Antikörper wurde für WB, FACS, IF (cc) und IF (p) validiert. Er ist geeignet, DVL1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für DVL1 Antikörper (AA 21-100) (Cy5.5) (ABIN670676)

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DVL1 Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-DVL1 Antikörper (Cy5.5)

Bindungsspezifität: AA 21-100

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DVL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DVL1

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Andere Bezeichnung: DVL1

Hintergrund:

Synonyms: DVL, DVL1L1, DVL1P1, Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1, DVL1

Background: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

Gen-ID: 1855

UniProt: O14640

Pathways: WNT Signalweg, Synaptic Membrane, Skeletal Muscle Fiber Development