DVL1 Antikörper (AA 21-100) (Biotin)
Kurzübersicht für DVL1 Antikörper (AA 21-100) (Biotin) (ABIN670673)
Target
Alle DVL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- AA 21-100
- 
                                            Kreuzreaktivität
- Human, Maus, Ratte
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- KLH conjugated synthetic peptide derived from human DVL1
- 
                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- 
                        WB 1:300-5000
 IHC-P 1:200-400
 IHC-F 1:100-500
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20°C for 12 months.
- 
                                            Haltbarkeit
- 12 months
 
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- 
    - DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
- 
                                            Andere Bezeichnung
- DVL1
- 
                                            Hintergrund
- 
                        Synonyms: DVL, DVL1L1, DVL1P1, Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1, DVL1 Background: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ). 
- 
                                            Gen-ID
- 1855
- 
                                            UniProt
- O14640
- 
                                            Pathways
- WNT Signalweg, Synaptic Membrane, Skeletal Muscle Fiber Development
 Target
- 
                    
 
                                     
                                     
                                    