TUBB3 Antikörper

Produktnummer ABIN6699201

Hersteller Produkt- Nr.: 212-301-e55

Produktdetails anti-TUBB3 Antikörper

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Hersteller Produkt- Nr.: 212-301-e55

Hersteller: Rockland

Verwendungszweck: Tubulin beta 3 Antibody

Kreuzreaktivität (Details): Anti-Tubulin beta 3 Antibody is directed against rat Tubulin beta III protein.

Aufreinigung: The antibody was Protein G purified from cell culture supernatant.

Immunogen: Anti-Tubulin beta 3 Monoclonal Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to beta III tubulin.

Klon: AA10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry_Dilution: 1:1,000

Western_Blot_Dilution: 1:10,000

Other: User Optimized

Kommentare:

Anti-Tubulin beta 3 (Mouse) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to beta III tubulin proteins in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Andere Bezeichnung: Tubulin beta 3 (TUBB3 Produkte)

Hintergrund:

Synonyms: mouse anti-Tubulin beta 3 Antibody, Neuron-specific class III beta-tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III

Background: Tubulin beta 3 Antibody detects Tubulin beta III protein. Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.

Gene Name: TUBB3

Gen-ID: 246118

UniProt: Q4QRB4

Pathways: Microtubule Dynamics, M Phase