Chromogranin A Antikörper (AA 420-457)

Produktnummer ABIN669846

Dieses Anti-Chromogranin A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Chromogranin A in ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human, Ratte, Maus und Huhn. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für Chromogranin A Antikörper (AA 420-457) (ABIN669846)

Target: Chromogranin A (CHGA)

Reaktivität: Human, Ratte, Maus, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chromogranin A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Chromogranin A Antikörper

Bindungsspezifität: AA 420-457

Kreuzreaktivität: Huhn, Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CGA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Chromogranin A Antikörper (ABIN669846)

Liu, Zhang, Zhang, Zhang, Hao, Song, Li, Feng, Hao, Shen, Min, Yang, Zhao: "Regulation of neuroendocrine cells and neuron factors in the ovary by zinc oxide nanoparticles." in: Toxicology letters, Vol. 256, pp. 19-32, (2016) (PubMed).

Liu, Nelson, Cromeens, Rager, Lannutti, Johnson, Besner: "HB-EGF embedded in PGA/PLLA scaffolds via subcritical CO2 augments the production of tissue engineered intestine." in: Biomaterials, Vol. 103, pp. 150-9, (2016) (PubMed).

Liu, Rager, Johnson, Enmark, Besner: "Enriched Intestinal Stem Cell Seeding Improves the Architecture of Tissue Engineered Intestine." in: Tissue engineering. Part C, Methods, (2015) (PubMed).

Wang, Ahmad, Sims, Magness, Allbritton: "In vitro generation of colonic epithelium from primary cells guided by microstructures." in: Lab on a chip, Vol. 14, Issue 9, pp. 1622-31, (2014) (PubMed).

Wang, Ahmad, Shah, Sims, Magness, Allbritton: "Capture and 3D culture of colonic crypts and colonoids in a microarray platform." in: Lab on a chip, Vol. 13, Issue 23, pp. 4625-34, (2013) (PubMed).

Details zu Chromogranin A

Target: Chromogranin A (CHGA)

Andere Bezeichnung: Chromogranin A

Hintergrund:

Synonyms: CGA, Chromogranin-A, Pituitary secretory protein I, SP-I, CHGA

Background: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008].

Gen-ID: 1113

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling