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CD31 Antikörper (AA 601-680) (FITC)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD31 in FACS, WB, IF (p) und IF (cc). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Schwein und Hund und wurde in 4+ Publikationen erwähnt.
Produktnummer ABIN669013

Kurzübersicht für CD31 Antikörper (AA 601-680) (FITC) (ABIN669013)

Target

Alle CD31 (PECAM1) Antikörper anzeigen
CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reaktivität

  • 389
  • 153
  • 79
  • 66
  • 43
  • 36
  • 20
  • 20
  • 11
  • 7
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
Human, Maus, Ratte, Kaninchen, Schwein, Hund

Wirt

  • 257
  • 175
  • 54
  • 8
  • 6
  • 3
  • 2
Kaninchen

Klonalität

  • 351
  • 145
  • 8
  • 1
Polyklonal

Konjugat

  • 200
  • 43
  • 32
  • 25
  • 19
  • 15
  • 15
  • 15
  • 15
  • 15
  • 15
  • 13
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD31 Antikörper ist konjugiert mit FITC

Applikation

  • 271
  • 247
  • 198
  • 133
  • 79
  • 71
  • 48
  • 36
  • 33
  • 33
  • 25
  • 23
  • 22
  • 13
  • 12
  • 9
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • Bindungsspezifität

    • 68
    • 20
    • 16
    • 15
    • 15
    • 12
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-680

    Kreuzreaktivität

    Hund, Human, Maus, Schwein, Kaninchen, Ratte

    Homologie

    Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from mouse CD31

    Isotyp

    IgG
  • Applikationshinweise

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Yang, Yu, Li, Yu, Ke, Wang, Wang, Qiu, Gao, Zhang, Huang: "Store-operated calcium entry-activated autophagy protects EPC proliferation via the CAMKK2-MTOR pathway in ox-LDL exposure." in: Autophagy, Vol. 13, Issue 1, pp. 82-98, (2017) (PubMed).

    Zhang, Chen, Liu, Zhou, Hu, Zhou, Han, Chen: "Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways." in: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 5, pp. 598-606, (2016) (PubMed).

    Zhou, Yang, Xin, Zhang, Hu, Zhou, Chen, Chen et al.: "Exendin-4 enhances the migration of adipose-derived stem cells to neonatal rat ventricular cardiomyocyte-derived conditioned medium via the phosphoinositide 3-kinase/Akt-stromal cell-derived ..." in: Molecular medicine reports, (2015) (PubMed).

    Yu, Wang, Wang, Lu, Li, Qin, Huang: "Activation of liver X receptor enhances the proliferation and migration of endothelial progenitor cells and promotes vascular repair through PI3K/Akt/eNOS signaling pathway activation." in: Vascular pharmacology, Vol. 62, Issue 3, pp. 150-61, (2014) (PubMed).

  • Target

    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

    Andere Bezeichnung

    CD31

    Hintergrund

    Synonyms: CD31, PECA1, GPIIA', PECAM-1, endoCAM, CD31/EndoCAM, Platelet endothelial cell adhesion molecule, PECAM1

    Background: Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-69 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).

    Gen-ID

    5175

    UniProt

    P16284

    Pathways

    Regulation of Actin Filament Polymerization
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