TIMP1 Antikörper (AA 103-207) (FITC)
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- Target Alle TIMP1 Antikörper anzeigen
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
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Bindungsspezifität
- AA 103-207
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Reaktivität
- Human, Ratte, Maus, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TIMP1 Antikörper ist konjugiert mit FITC
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human, Maus, Kaninchen, Ratte
- Homologie
- Dog,Cow,Sheep,Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TIMP-1
- Isotyp
- IgG
- Top Product
- Discover our top product TIMP1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Andere Bezeichnung
- TIMP-1 (TIMP1 Produkte)
- Synonyme
- TIMP-1 antikoerper, TIMP1 antikoerper, DKFZp468A0912 antikoerper, CLGI antikoerper, EPA antikoerper, EPO antikoerper, HCI antikoerper, TIMP antikoerper, Timp antikoerper, Clgi antikoerper, TIMP metallopeptidase inhibitor 1 antikoerper, tissue inhibitor of metalloproteinase 1 antikoerper, TIMP1 antikoerper, Timp1 antikoerper
- Hintergrund
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Synonyms: EPA, EPO, HCI, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1
Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP1, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro, but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
- Gen-ID
- 7076
- UniProt
- P01033
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