MAP2K5 Antikörper (pSer311, pThr315)

Produktnummer ABIN6658265

Hersteller Produkt- Nr.: 612-401-d74

Dieses Anti-MAP2K5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MAP2K5 in WB. Geeignet für Ratte.

Kurzübersicht für MAP2K5 Antikörper (pSer311, pThr315) (ABIN6658265)

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP2K5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAP2K5 Antikörper

Bindungsspezifität: pSer311, pThr315

Hersteller Produkt- Nr.: 612-401-d74

Hersteller: Rockland

Verwendungszweck: MEK5 phospho S311/phospho T315 Antibody

Kreuzreaktivität (Details): MEK5 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Aufreinigung: Anti-MEK5 pS311/pT315 antibody is directed against rat MEK5.

Immunogen: Anti-MEK5 pS311/pT315 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser311/Thr315 conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1:1000

Kommentare:

Anti-MEK5 pS311/pT315 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 49 kDa in size corresponding to MEK5 protein phosphorylated at Ser311/Thr315 in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu MAP2K5

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Andere Bezeichnung: MEK5

Hintergrund:

Synonyms: Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5

Background: MEK5 pS311/pT315 antibody detects MEK5 that is phosphorylated at Ser311 and Threonine315. MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 whereas MEK5 itself is regulated by MEKK3. An important link between MEK5 and metastatic prostrate cancer has been demonstrated. Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation. Therefore, MEK5 pS311/pT315 antibody is ideal for investigators involved in Cell Signaling, Cell Migration and Proliferation and, more generally in Cancer Research.

Gene Name: MAP2K5

Gen-ID: 29568

UniProt: Q62862

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung