SYN1 Antikörper (pSer549)

Produktnummer ABIN6658253

Hersteller Produkt- Nr.: 612-401-c94

Dieses Anti-SYN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SYN1 in WB und IHC. Geeignet für Ratte.

Kurzübersicht für SYN1 Antikörper (pSer549) (ABIN6658253)

Target: SYN1 (Synapsin I (SYN1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SYN1 Antikörper

Bindungsspezifität: pSer549

Hersteller Produkt- Nr.: 612-401-c94

Hersteller: Rockland

Verwendungszweck: Synapsin I phospho S549 Antibody

Kreuzreaktivität (Details): Anti-Synapsin I pS549 antibody is directed against rat Synapsin I.

Aufreinigung: Synapsin I pS549 was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-Synapsin I pS549 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser549 of Synapsin I.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry_Dilution: 1:500

Western_Blot_Dilution: 1:1000

Kommentare:

Suggested Applications: Titrated value sufficient to run approximately 10 mini blots.
Anti-Synapsin pS549 (Rabbit) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 78 kDa in size corresponding to synapsin I doublet phosphorylated at Ser549 in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu SYN1

Target: SYN1 (Synapsin I (SYN1))

Andere Bezeichnung: Synapsin I

Hintergrund:

Synonyms: Synapsin I, SYN1

Background: Synapsin I pS549 antibody is directed against rat Synapsin I, which plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Ser 549 along with Ser 62 and Ser 67 are the sites of synapsin I that are phosphorylated by MAP kinase. Phosphorylation and subsequent dephosphorylation of this site is thought to play a key role in synaptic vesicle trafficking. Anti-Synapsin I pS549 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: SYN1

Gen-ID: 24949

NCBI Accession: NP_001104252

UniProt: P09951