Kv2.2 Antikörper (N-Term)

Produktnummer ABIN6658108

Produktdetails anti-Kv2.2 Antikörper

Target: Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))

Bindungsspezifität: N-Term

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Kv2.2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Anti-Kv2.2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv2.2 from Mouse, human, and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Kv2.2 from other sources has not been determined. Ion Channels research.

Immunogen:

Immunogen: Kv2.2 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to the n-terminus region of rat kv2.2.

Immunogen Type: Recombinant Protein

Klon: S37-89

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-Kv2.2 Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~125 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Western Blot Dilution: 1 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu Kv2.2

Target: Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))

Andere Bezeichnung: Kv2.2 (KCNB2 Produkte)

Synonyme: KCNB2 antikoerper, si:ch211-193n21.1 antikoerper, Kv2.2 antikoerper, 9630047L19Rik antikoerper, BB130875 antikoerper, XShab12 antikoerper, kcnb2 antikoerper, KV2.2 antikoerper, potassium voltage-gated channel subfamily B member 2 antikoerper, potassium voltage-gated channel, Shab-related subfamily, member 2 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 2 antikoerper, potassium voltage gated channel, Shab-related subfamily, member 2 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 2 S homeolog antikoerper, KCNB2 antikoerper, kcnb2 antikoerper, LOC100051372 antikoerper, Kcnb2 antikoerper, kcnb2.S antikoerper

Hintergrund:

Synonyms: KCNB2, potassium voltage gated channel subfamily B member 2, CDRK, Voltage-gated potassium channel subunit Kv2.2

Background: Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alpha- subunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1-KV4 subfamilies generate functional K+ channels in a homotetrameric configuration. The KV2 subfamily consists of KV2.1 and KV2.2, and both have very similar properties. Members of the KV2 subfamily are widely expressed in neuronal tissues. They have also been reported in neurons in the dorsal root ganglia.

Gene Name: Kcnb2

Gen-ID: 117105

NCBI Accession: NP_446452

UniProt: G3V9F1