COX IV Antikörper (pSer58)

Produktnummer ABIN6657951

Hersteller Produkt- Nr.: 600-401-x00

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COX IV in WB und ELISA. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für COX IV Antikörper (pSer58) (ABIN6657951)

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX IV Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-COX IV Antikörper

Bindungsspezifität: pSer58

Hersteller Produkt- Nr.: 600-401-x00

Hersteller: Rockland

Verwendungszweck: CoxIV phospho S58 Antibody

Aufreinigung: Anti-Phospho-Ser58 COXIV Antibody was prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.

Sterilität: Sterile filtered

Immunogen: Anti-Phospho-Ser58 COXIV Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser58 of mouse COXIV protein conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-Phospho-Ser58 COXIV Antibody has been tested by Western Blots and is specific for the ~17k COXIV-1 protein phosphorylated at Ser58. Immunolabeling is blocked by the phospho-peptide used as antigen but not by the corresponding dephospho-peptide. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Preservative: None

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu COX IV

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Andere Bezeichnung: COXIV

Hintergrund:

Synonyms: Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1

Background: COX, also known as cytochrome c oxidase, has 12 subunits that make up the transmembrane mitochondrial protein. Subunit IV has two isoforms, COXIV-1 and COXIV-2. COXIV-1 is expressed ubiquitously while COXIV-2 is highly expressed in adult lung and low levels in brain and heart. Phosphorylation of amino acid residue ser58 of the COXIV-1 protein is a PKA-dependent regulation of COX and plays an important role in metabolism and CREB cycle activation. COX IV pS58 Antibody is ideal for researchers interested in cell cycle research.

Gene Name: COX4i1

Gen-ID: 12857

NCBI Accession: NP_034071

UniProt: P19783

Pathways: Proton Transport