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NK-1.1/CD161c Antikörper (PE)

Der Maus Monoklonal Anti-NK-1.1/CD161c-Antikörper wurde für FACS, IP und IHC validiert. Er ist geeignet, NK-1.1/CD161c in Proben von Maus zu detektieren.
Rockland
Produktnummer ABIN6657871
Hersteller Produkt- Nr.: 200-308-n93

Kurzübersicht für NK-1.1/CD161c Antikörper (PE) (ABIN6657871)

Target

NK-1.1/CD161c (NK-1.1)

Reaktivität

  • 63
  • 16
  • 1
Maus

Wirt

  • 41
  • 17
  • 6
Maus

Klonalität

  • 46
  • 16
  • 2
Monoklonal

Konjugat

  • 13
  • 5
  • 5
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NK-1.1/CD161c Antikörper ist konjugiert mit PE

Applikation

  • 55
  • 17
  • 13
  • 10
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Klon

PK136
  • Hersteller Produkt- Nr.

    200-308-n93

    Hersteller

    Rockland

    Verwendungszweck

    NK1.1 Phycoerythrin Antibody

    Aufreinigung

    Phycoerythrin conjugated NK1.1 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse NK1.

    Sterilität

    Sterile filtered

    Immunogen

    Anti-NK1.1 Antibody (Monoclonal) was produced by repeated immunizations with NK-1+ cells from mouse spleen and bone marrow.

    Isotyp

    IgG2a kappa

    Labeling Ratio

    1-2
  • Applikationshinweise

    Immunoprecipitation_Dilution: User Optimized

    Immunohistochemistry_Dilution: User Optimized

    Flow_Cytometry_Dilution: 10 μL/10^6 cells (0.1 μg)

    Kommentare

    Anti-NK1.1 tested in Flow Cytometry and is useful for Immunohistochemistry, Immunoprecipitation using mouse spleen cells, or an appropriate cell type (where indicated). Researchers should determine optimal titers for applications that are not stated.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.09 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

    Haltbarkeit

    6 months
  • Target

    NK-1.1/CD161c (NK-1.1)

    Andere Bezeichnung

    NK1.1

    Hintergrund

    Synonyms: Killer cell lectin-like receptor subfamily B member 1C, CD161 antigen-like family member C, Lymphocyte antigen 55c, Ly-55c, NK1.1, NKR-P1.9, NKR-P1C, Natural killer cell surface protein P1-40, NKR-P1 40, CD161c, Klrb1c, Ly55c, Nkrp1c

    Background: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

    Gene Name: Klrb1c

    Gen-ID

    17059

    NCBI Accession

    NP_001153376

    UniProt

    P27814
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