NK-1.1/CD161c Antikörper (FITC)

Produktnummer ABIN6657870

Hersteller Produkt- Nr.: 200-302-n93

Dieser Maus Monoklonal Antikörper detektiert spezifisch NK-1.1/CD161c in FACS, IP, IHC und FM. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für NK-1.1/CD161c Antikörper (FITC) (ABIN6657870)

Target: NK-1.1/CD161c (NK-1.1)

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NK-1.1/CD161c Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Klon: PK136

Produktdetails anti-NK-1.1/CD161c Antikörper (FITC)

Hersteller Produkt- Nr.: 200-302-n93

Hersteller: Rockland

Verwendungszweck: NK1.1 Fluorescein Antibody

Aufreinigung: Fluorescein conjugated NK1.1 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse NK1.

Sterilität: Sterile filtered

Immunogen: Anti-NK1.1 Antibody (Monoclonal) was produced by repeated immunizations with NK1.1 antigen.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: User Optimized

Flow_Cytometry_Dilution: 10 μL/10^6 cells (0.1 μg)

IF_Microscopy_Dilution: User Optimized

Other: Sufficient to run approximately 500 tests

Kommentare:

Anti-NK1.1 has been tested by Flow Cytometry and is useful for Immunohistochemistry, Immunoprecipitation, Immunofluorescence using mouse spleen cells, or an appropriate cell type (where indicated). Researchers should determine optimal titers for applications that are not stated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.1 % Gelatin

Preservative: 0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

Haltbarkeit: 6 months

Details zu NK-1.1/CD161c

Target: NK-1.1/CD161c (NK-1.1)

Andere Bezeichnung: NK1.1

Hintergrund:

Synonyms: Killer cell lectin-like receptor subfamily B member 1C, CD161 antigen-like family member C, Lymphocyte antigen 55c, Ly-55c, NK1.1, NKR-P1.9, NKR-P1C, Natural killer cell surface protein P1-40, NKR-P1 40, CD161c, Klrb1c, Ly55c, Nkrp1c

Background: The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1. The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1.

Gene Name: Klrb1c

Gen-ID: 17059

NCBI Accession: NP_001153376

UniProt: P27814