TFAM Antikörper (C-Term)

Produktnummer ABIN6657693

Hersteller Produkt- Nr.: 100-401-x30

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TFAM in WB und ELISA. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für TFAM Antikörper (C-Term) (ABIN6657693)

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TFAM Antikörper

Bindungsspezifität: C-Term

Hersteller Produkt- Nr.: 100-401-x30

Hersteller: Rockland

Verwendungszweck: TFAM Antibody

Aufreinigung: Anti-TFAM Antibody is a prepared sterile filtered neat serum.

Sterilität: Sterile filtered

Immunogen: Anti-TFAM Antibody was produced in rabbits by repeated immunizations with a native recombinant mouse TFAM protein with c-terminal 6-his tag.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:20,000

Western_Blot_Dilution: 1:2000

Kommentare:

Anti-TFAM Antibody has been tested in Western Blots and is specific for the ~24 kDa TFAM protein. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: None

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.

Haltbarkeit: 12 months

Details zu TFAM

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Andere Bezeichnung: TFAM

Hintergrund:

Synonyms: Transciption factor A mitochondrial, mtTFA, Testis-specific high mobility group protein, TS-HMG

Background: Mitochondrial Transcription Factor A (TFAM) is a key activator of mitochondrial (mt) DNA transcription as well as a participant in mitochondrial genome replication. mtDNA is highly susceptible to oxidative stress leading to mitochondrial dysfunction. Overexpression of TFAM has been implicated in the amelioration of age dependent impairment of brain functions through the prevention of oxidative stress and mitochondrial dysfunction in microglia. More recently, TFAM overexpression has been shown to potentially reduce oxidative stress in motor neurons and delay onset of amyotrophic lateral sclerosis (ALS) in ALS model mice. TFAM Antibody is ideal for researchers interested in neuroscience research.

Gene Name: TFAM

Gen-ID: 21780

NCBI Accession: NP_033386

UniProt: P40630

Pathways: Chromatin Binding