TFAM Antikörper (AA 1-220)

Produktnummer ABIN6149024

Produktdetails anti-TFAM Antikörper

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Bindungsspezifität: AA 1-220

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Sequenz: MAFLRSMWGV LSALGRSGAE LCTGCGSRLR SPFSFVYLPR WFSSVLASCP KKPVSSYLRF SKEQLPIFKA QNPDAKTTEL IRRIAQRWRE LPDSKKKIYQ DAYRAEWQVY KEEISRFKEQ LTPSQIMSLE KEIMDKHLKR KAMTKKKELT LLGKPKRPRS AYNVYVAERF QEAKGDSPQE KLKTVKENWK NLSDSEKELY IQHAKEDETR YHNEMKSWEE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TFAM (NP_003192.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,ChIP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TFAM

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Andere Bezeichnung: TFAM (TFAM Produkte)

Synonyme: tcf6 antikoerper, mttf1 antikoerper, mttfa antikoerper, tcf6l1 antikoerper, tcf6l2 antikoerper, tcf6l3 antikoerper, mttfa-A antikoerper, xl-mtTFA antikoerper, MGC153358 antikoerper, zgc:153358 antikoerper, MTTF1 antikoerper, MTTFA antikoerper, TCF6 antikoerper, TCF6L1 antikoerper, TCF6L2 antikoerper, TCF6L3 antikoerper, AI661103 antikoerper, Hmgts antikoerper, mtTFA antikoerper, tsHMG antikoerper, Mttfa antikoerper, transcription factor A, mitochondrial antikoerper, transcription factor A, mitochondrial L homeolog antikoerper, TFAM antikoerper, tfam.L antikoerper, tfam antikoerper, Tfam antikoerper

Hintergrund: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.,TFAM,MTDPS15,MTTF1,MTTFA,TCF6,TCF6L1,TCF6L2,TCF6L3,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Wnt/β-Catenin Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Mitochondrial markers,Nucleotide metabolism,Molecular processes,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,Cardiogenesis,TFAM

Molekulargewicht: 25 kDa/29 kDa

Gen-ID: 7019

UniProt: Q00059

Pathways: Chromatin Binding