Involucrin Antikörper
Kurzübersicht für Involucrin Antikörper (ABIN6657536)
Target
Alle Involucrin (IVL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Hersteller Produkt- Nr.
- 200-301-p39
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Hersteller
- Rockland
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Verwendungszweck
- Involucrin Antibody
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Kreuzreaktivität (Details)
- This product reacts with human and pig.
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Aufreinigung
- Anti-Involucrin antibody was purified from mouse ascites by protein A chromatography.
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Immunogen
- Involucrin antibody was produced in mice by repeated immunizations with human involucrin.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA_Dilution: 1:20,000
Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 1 μg/mL
Other: Immunocytochemistry: 1 μg/mL
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Kommentare
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Anti-Involucrin is tested for Immunohistochemistry -P, -F, Immunocytochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~68.5 kDa corresponding to the appropriate cell lysate or extract.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
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Reconstitution_Buffer: Neutral PBS
Reconstitution_Volume: 1.0 mL
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Buffer
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Buffer: 1.2 % sodium acetate
Stabilizer: 2 mg BSA
Preservative: 0.01 % (w/v) Sodium Azide -
Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Haltbarkeit
- 12 months
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- Involucrin (IVL)
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Andere Bezeichnung
- Involucrin
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Hintergrund
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Synonyms: INVO, IVL, Involucrin Antibody
Background: Involucrin is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. The gene consists of 585 amino acids, 390 of which form a central decapeptide repeat, rich in glutamine and glutamic acid. The involucrin gene, encoding a protein of the terminally differentiated keratinocyte, is polymorphic in the human. Involucrin has previously been mapped to chromosome 1q21. The epidermal protein involucrin has been remodeled in the higher primates. And the existence of two populations of East Asian involucrin alleles gives support for the existence of a Eurasian stem lineage from which Caucasians and a part of the Asian population originated. This antibody is suitable for researchers interested in skin cell research.
Gene Name: IVL
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Gen-ID
- 3713
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NCBI Accession
- NP_005538
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UniProt
- P07476
Target
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