Caldesmon Antikörper
Kurzübersicht für Caldesmon Antikörper (ABIN6657487)
Target
Alle Caldesmon (CALD1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Hersteller Produkt- Nr.
- 200-301-p24
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Hersteller
- Rockland
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Verwendungszweck
- Caldesmon (smooth) Antibody
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Kreuzreaktivität (Details)
- This product reacts with human, mouse, and rabbit.
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Aufreinigung
- Anti-Caldesmon antibody was purified from mouse ascites by protein A chromatography.
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Sterilität
- Sterile filtered
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Immunogen
- Caldesmon (smooth) antibody was produced in mice by repeated immunizations with human uterus smooth muscle extract.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA_Dilution: 1:20,000
Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 1-2 μg/mL
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Kommentare
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Anti-Caldesmon is tested for Immunohistochemistry -P and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~93.2 kDa with isoforms ~60kDa corresponding to the appropriate cell lysate or extract.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Buffer: 1.2 % sodium acetate
Stabilizer: 2 mg BSA
Preservative: 0.01 % (w/v) Sodium Azide -
Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Haltbarkeit
- 12 months
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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Andere Bezeichnung
- Caldesmon (smooth)
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Hintergrund
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Synonyms: CDM, H-CAD, L-CAD
Background: Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells. The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons. This antibody is suitable for researchers interested in neurodegenerative diseases, developmental signaling, GPCR signaling, and MAK Kinase Signaling.
Gene Name: CALD1
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Gen-ID
- 800
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NCBI Accession
- NP_004333
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UniProt
- Q05682
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Pathways
- Myometrial Relaxation and Contraction
Target
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