Retinoid X Receptor gamma Antikörper (N-Term)
Kurzübersicht für Retinoid X Receptor gamma Antikörper (N-Term) (ABIN6657359)
Target
Alle Retinoid X Receptor gamma (RXRG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- N-Term
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Hersteller Produkt- Nr.
- 209-301-e28
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Hersteller
- Rockland
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Verwendungszweck
- Retinoid X Receptor gamma Antibody
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Kreuzreaktivität (Details)
- Retinoic Acid Receptor gamma antibody was Protein G purified from cell culture supernatant.
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Aufreinigung
- Anti-Retinoic Acid Receptor gamma antibody detects Retinoic Acid Receptor gamma.
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Immunogen
- Anti-Retinoic Acid Receptor gamma was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the hinged region of RAR-gamma.
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Isotyp
- IgG1
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Applikationshinweise
- Optional[Neutralization_Dilution]: 1:1000
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Kommentare
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Anti-Retinoid X Receptor gamma antibody is tested for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to the RXR-γ isotype in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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Haltbarkeit
- 12 months
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- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
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Andere Bezeichnung
- Retinoid X Receptor gamma
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Hintergrund
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Synonyms: mouse anti-Retinoid X Receptor gamma Antibody, mouse anti-RXRG antibody, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma
Background: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
Gene Name: RXRG
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Gen-ID
- 6258
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UniProt
- P48443
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Target
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