Retinoid X Receptor gamma Antikörper (Retinoid X Receptor, gamma) (C-Term)

Details for Product anti-RXRG Antibody No. ABIN2780815
Antigen
  • NR2B3
  • RXRC
  • zgc:92183
  • RXRgamma
  • RXRG
  • RXR-gamma
  • nr2b3
  • xrxrg
  • rxrc
  • Nr2b3
  • retinoid X receptor gamma
  • retinoid X receptor, gamma b
  • retinoid X receptor gamma L homeolog
  • RXRG
  • rxrgb
  • rxrg.L
  • rxrg
  • Rxrg
  • RXRGAMMA
Epitop
C-Term
15
5
4
4
3
3
2
2
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
108
55
46
13
11
9
6
5
3
3
1
1
1
1
1
Wirt
Kaninchen
77
17
14
Klonalität
Polyklonal
Konjugat
Dieser Retinoid X Receptor gamma Antikörper ist unkonjugiert
5
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
71
42
18
13
13
10
5
4
4
2
1
1
Optionen
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human RXRG
Sequenz LEAYTKQKYP EQPGRFAKLL LRLPALRSIG LKCLEHLFFF KLIGDTPIDT
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
Produktmerkmale This is a rabbit polyclonal antibody against RXRG. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Protein A purified
Plasmids, Primers & others Plasmide, Primers & weitere Retinoid X Receptor gamma products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung RXRG (RXRG Antibody Abstract)
Hintergrund RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: NR2B3, RXRC
Protein Interaction Partner: NR1H3, NR1H2, RARB, RARA, MPPED2, UBC, CUL1, DCK, NR1H4, NCOR2, NR1I2, VDR, THRB, RARG, PPARD, MAP4, CAMK2B, CEBPZ, HOXD4, AJUBA, RPAP2, LRSAM1, PNO1, CHGB, THRA, NCOA6, PPARG, SRF, CREBBP, PPARA, NR4A1, Nr0b2, ITGB3BP,
Protein Size: 463
Molekulargewicht 51 kDa
Gen-ID 6258
NCBI Accession NM_006917, NP_008848
UniProt P48443
Pathways Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 463 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Retinoid X Receptor, gamma (RXRG) (C-Term) antibody (ABIN2780815) WB Suggested Anti-RXRG Antibody Titration: 2.5ug/ml Positive Control: Jurkat cell ...
Western Blotting (WB) image for anti-Retinoid X Receptor, gamma (RXRG) (C-Term) antibody (ABIN2780815) Host: Mouse Target Name: RXRG Sample Tissue: Mouse Spleen Antibody Dilution: 1...
Produkt verwendet in: Bungard, McGivan: "Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers." in: Archives of biochemistry and biophysics, Vol. 443, Issue 1-2, pp. 53-9, 2005 (PubMed).

Allgemeine Veröffentlichungen ROSENKRANTZ: "An antimony trichloride reagent suitable for the detection and estimation of nonketonic steroids." in: Archives of biochemistry and biophysics, Vol. 44, Issue 1, pp. 1-8, 1953 (PubMed).

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