Lamin A/C Antikörper

Produktnummer ABIN6656055

Hersteller Produkt- Nr.: 200-301-x12

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Lamin A/C in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Lamin A/C Antikörper (ABIN6656055)

Target: Lamin A/C (LMNA)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Lamin A/C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 4C4

Produktdetails anti-Lamin A/C Antikörper

Hersteller Produkt- Nr.: 200-301-x12

Hersteller: Rockland

Verwendungszweck: Lamin A/C Antibody

Aufreinigung: Anti-Lamin A/C Antibody was purified from tissue culture supernatant by protein G chromatography.

Sterilität: Sterile filtered

Immunogen: Anti-Lamin A/C Antibody was produced in mice by repeated immunizations with a recombinant full length human lamin C expressed in and purified from E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:50,000

Immunohistochemistry_Dilution: 1:1000

Western_Blot_Dilution: 1:5000

Other: ICC: 1:1000

Kommentare:

Anti-Lamin A/C Antibody is tested for Western Blot, Immunocytochemistry, and Immunohistochemistry, and it is specific for the ~64 and 74 kDa lamin A and C proteins. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.

Haltbarkeit: 12 months

Details zu Lamin A/C

Target: Lamin A/C (LMNA)

Andere Bezeichnung: Lamin A/C

Hintergrund:

Synonyms: Prelamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMN1

Background: Lamins A and C are nuclear structural proteins that are part of the intermediate filament family and coded for by the same gene (LMNA). Lamins A and C are nearly identical except for their carboxy termini. Mutations in the gene encoding lamins A/C have been shown to cause a variety of diseases including autosomal dominant Emery-Dreifuss muscular dystrophy, autosomal dominant limb-girdle muscular dystrophy and Charcot-Marie-Tooth disorder type 2. Lamin A/C Antibody is ideal for researchers interested in cancer research.

Gene Name: LMNA

Gen-ID: 4000

UniProt: P02545

Pathways: Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus