CD27 Antikörper (FITC)

Produktnummer ABIN6655550

Produktdetails anti-CD27 Antikörper (FITC)

Target: CD27 (CD27 Molecule (CD27))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD27 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Kreuzreaktivität (Details): Cross reactivity with CD27 from other sources has not been tested

Aufreinigung: Fluorescein conjugated CD27 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD27. Reactivity is observed against human CD27, Baboon, Cynomolgus, Rhesus, and Squirrel Monkey. . Anti-CD27 is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC.

Immunogen:

Immunogen: Anti-CD27 Antibody (Monoclonal) was produced by repeated immunizations with CD27 antigen.

Klon: O323

Isotyp: IgG1

Labeling Ratio: 4-6

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-CD27 is useful for Flow Cytometry. Researchers should determine optimal titers for applications that are not stated.

Flow Cytometry Dilution: 5 µL/1x10e6 cells or 100μL of whole blood

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.2 % BSA (w/v)

0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

Referenzen für anti-CD27 Antikörper (FITC) (ABIN6655550)

Agematsu, Kobata, Sugita, Hirose, Schlossman, Morimoto: "Direct cellular communications between CD45R0 and CD45RA T cell subsets via CD27/CD70." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 8, pp. 3627-35, (1995) (PubMed).

Hintzen, de Jong, Lens, van Lier: "CD27: marker and mediator of T-cell activation?" in: Immunology today, Vol. 15, Issue 7, pp. 307-11, (1994) (PubMed).

Details zu CD27

Target: CD27 (CD27 Molecule (CD27))

Andere Bezeichnung: CD27 (CD27 Produkte)

Synonyme: TNFRSF7 antikoerper, S152 antikoerper, Tnfrsf7 antikoerper, Tp55 antikoerper, S152. LPFS2 antikoerper, T14 antikoerper, CD27 molecule antikoerper, CD27 antigen antikoerper, CD27 antikoerper, Cd27 antikoerper

Hintergrund:

Synonyms: CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, TNFRSF7

Background: CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-kB and SAPK/JNK activation.

Gene Name: CD27

Gen-ID: 939

NCBI Accession: NP_001233

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints