KDM4A Antikörper (Internal Region)

Produktnummer ABIN6655514

Hersteller Produkt- Nr.: 600-401-x45

Dieses Anti-KDM4A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KDM4A in WB und ELISA. Geeignet für Human.

Kurzübersicht für KDM4A Antikörper (Internal Region) (ABIN6655514)

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-KDM4A Antikörper

Bindungsspezifität: Internal Region

Hersteller Produkt- Nr.: 600-401-x45

Hersteller: Rockland

Verwendungszweck: JMJD2A Antibody

Kreuzreaktivität (Details): Cross reactivity with other species was not tested.

Aufreinigung: Anti-JMJD2a Antibody was purified by affinity purification.

Sterilität: Sterile filtered

Immunogen: Anti-JMJD2a Antibody was produced in rabbits by repeated immunizations with a synthetic peptide from human JMJD2a containing a sequence from the internal part of the protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:100 - 1:500

Western_Blot_Dilution: 1:500

Kommentare:

Anti-JMJD2a Antibody is tested for ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 121 kDa in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300

Konservierungsmittel: ProClin, Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu KDM4A

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Andere Bezeichnung: JMJD2a

Hintergrund:

Synonyms: Lysine-specific demethylase 4A, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, JHDM3A, JMJD2, KIAA0677

Background: JMJD2a, belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no activity towards H3K4, H3K27 and H4K20, or to the mono- and dimethylated H3K9 and H3K36. JMJD2a plays a role in the transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. Anti-JMJD2a Antibody is ideal for research in Chromatin Remodeling, Gene Expression and Epigenetics.

Gene Name: KDM4A

Gen-ID: 9682

NCBI Accession: NP_055478

UniProt: O75164

Pathways: Warburg Effekt